Our client, an establish privately owned biotech company that manufacture high purity biopharmaceutical products currently have an opportunity for a Senior Process Development Scientist to join their team. The role will be responsible for synthesising a range of peptides and peptide conjugates to support the polyclonal antibofy programme. The role will also co-ordinate the delivery of a variety of polyclonal antibody projects, through process development and technical transfer into the GMP production facility.
Responsibilities:
The main duties include:
- Lead the synthesis and purification activities to produce high quality peptide products
- Co-ordinate process development of polyclonal antibody projects (and project re-makes) to enable smooth transition into GMP production
- Provide a high level of specialist technical knowledge and hands-on training
- Prepare project specific development documentation to a high standard e.g. SOPs, development protocols and associated reports, batch records
- Adhere to company Quality and Health and Safety Policies
Skills/Experience Required:
Essential:
- Degree in relevant scientific discipline
- Extensive hands-on bench experience in peptide synthesis, purification and analysis
- Extensive experience in downstream processing and scale up, to include: column chromatography, Tangential Flow Filtration
- Experience in protein analytical methods i.e. SDS-PAGE, protein assays, UV assays, HPLC
- Competent in word processing, spreadsheet and database entry skills
- Experience in writing technical documents, e.g. development reports, batch records, SOPs
Desirable
- Use of PurePep Chorus Peptide Synthesiser
- Experience in bioconjugation of peptide
- Use of AKTA (or similar) system in protein purification and scale-up
- Experience in technology transfer of products/processes
- Knowledge of ELISA methodology for protein analysis
Personal Attributes:
- Excellent oral and written communication skills
- Excellent attention to detail
- The ability to work independently and within a team environment
- Ability to solve complex problems with focus on continuous improvement
- Ability to adapt to rapidly changing demands
Please apply online in the first instance.
STEM Recruitment Solutions Ltd operates as a Recruitment Agency in this instance. We endeavour to reply to all applications when possible.